Post-Therapeutic Relapse of Psoriasis after CD11a Blockade Is Associated with T Cells and Inflammatory Myeloid DCs

To understand the development of new psoriasis lesions, we studied a group of moderate-to-severe psoriasis patients who experienced a relapse after ceasing efalizumab (anti-CD11a, Raptiva, Genentech). There were increased CD3(+) T cells, neutrophils, CD11c(+) and CD83(+) myeloid dendritic cells (DCs...

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Detalles Bibliográficos
Autores principales: Johnson-Huang, Leanne M., Pensabene, Cara A., Shah, Kejal R., Pierson, Katherine C., Kikuchi, Toyoko, Lentini, Tim, Gilleaudeau, Patricia, Sullivan-Whalen, Mary, Cueto, Inna, Khatcherian, Artemis, Hyder, Luke A., Suárez-Fariñas, Mayte, Krueger, James G., Lowes, Michelle A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277585/
https://www.ncbi.nlm.nih.gov/pubmed/22348003
http://dx.doi.org/10.1371/journal.pone.0030308

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3277585/
https://www.ncbi.nlm.nih.gov/pubmed/22348003
http://dx.doi.org/10.1371/journal.pone.0030308

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