P190B RhoGAP Regulates Chromosome Segregation in Cancer Cells

Rho GTPases are overexpressed and hyperactivated in many cancers, including breast cancer. Rho proteins, as well as their regulators and effectors, have been implicated in mitosis, and their altered expression promotes mitotic defects and aneuploidy. Previously, we demonstrated that p190B Rho GTPase...

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Detalles Bibliográficos
Autores principales: Hwang, Melissa, Peddibhotla, Sirisha, McHenry, Peter, Chang, Peggy, Yochum, Zachary, Park, Ko Un, Sears, James Cooper, Vargo-Gogola, Tracy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348653/
https://www.ncbi.nlm.nih.gov/pubmed/22582143
http://dx.doi.org/10.3390/cancers4020475

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3348653/
https://www.ncbi.nlm.nih.gov/pubmed/22582143
http://dx.doi.org/10.3390/cancers4020475

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