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MicroRNA-146a Is Upregulated by and Negatively Regulates TLR2 Signaling
TLR signaling is a crucial component of the innate immune response to infection. MicroRNAs (miRNAs) have been shown to be upregulated during TLR signaling. Specifically, microRNA-146a (miR-146a) plays a key role in endotoxin tolerance by downregulating interleukin-1 receptor-associated kinase 1 (IRA...
Autores principales: | Quinn, Edel M., Wang, Jiang Huai, O’Callaghan, Grace, Redmond, H. Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3639252/ https://www.ncbi.nlm.nih.gov/pubmed/23638011 http://dx.doi.org/10.1371/journal.pone.0062232 |
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