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Improving mammalian genome scaffolding using large insert mate-pair next-generation sequencing

BACKGROUND: Paired-tag sequencing approaches are commonly used for the analysis of genome structure. However, mammalian genomes have a complex organization with a variety of repetitive elements that complicate comprehensive genome-wide analyses. RESULTS: Here, we systematically assessed the utility...

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Detalles Bibliográficos
Autores principales: van Heesch, Sebastiaan, Kloosterman, Wigard P, Lansu, Nico, Ruzius, Frans-Paul, Levandowsky, Elizabeth, Lee, Clarence C, Zhou, Shiguo, Goldstein, Steve, Schwartz, David C, Harkins, Timothy T, Guryev, Victor, Cuppen, Edwin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3648348/
https://www.ncbi.nlm.nih.gov/pubmed/23590730
http://dx.doi.org/10.1186/1471-2164-14-257