ROS play a critical role in the differentiation of alternatively activated macrophages and the occurrence of tumor-associated macrophages
Differentiation to different types of macrophages determines their distinct functions. Tumor-associated macrophages (TAMs) promote tumorigenesis owing to their proangiogenic and immune-suppressive functions similar to those of alternatively activated (M2) macrophages. We report that reactive oxygen...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698641/ https://www.ncbi.nlm.nih.gov/pubmed/23752925 http://dx.doi.org/10.1038/cr.2013.75 |