ROS play a critical role in the differentiation of alternatively activated macrophages and the occurrence of tumor-associated macrophages

Differentiation to different types of macrophages determines their distinct functions. Tumor-associated macrophages (TAMs) promote tumorigenesis owing to their proangiogenic and immune-suppressive functions similar to those of alternatively activated (M2) macrophages. We report that reactive oxygen...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhang, Yan, Choksi, Swati, Chen, Kun, Pobezinskaya, Yelena, Linnoila, Ilona, Liu, Zheng-Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3698641/
https://www.ncbi.nlm.nih.gov/pubmed/23752925
http://dx.doi.org/10.1038/cr.2013.75