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Prion Replication Occurs in Endogenous Adult Neural Stem Cells and Alters Their Neuronal Fate: Involvement of Endogenous Neural Stem Cells in Prion Diseases

Prion diseases are irreversible progressive neurodegenerative diseases, leading to severe incapacity and death. They are characterized in the brain by prion amyloid deposits, vacuolisation, astrocytosis, neuronal degeneration, and by cognitive, behavioural and physical impairments. There is no treat...

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Detalles Bibliográficos
Autores principales: Relaño-Ginès, Aroa, Gabelle, Audrey, Hamela, Claire, Belondrade, Maxime, Casanova, Danielle, Mourton-Gilles, Chantal, Lehmann, Sylvain, Crozet, Carole
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3731238/
https://www.ncbi.nlm.nih.gov/pubmed/23935493
http://dx.doi.org/10.1371/journal.ppat.1003485