Human Lactate Dehydrogenase A Inhibitors: A Molecular Dynamics Investigation

Lactate dehydrogenase A (LDHA) is an important enzyme in fermentative glycolysis, generating most energy for cancer cells that rely on anaerobic respiration even under normal oxygen concentrations. This renders LDHA a promising molecular target for the treatment of various cancers. Several efforts h...

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Detalles Bibliográficos
Autores principales: Shi, Yun, Pinto, B. Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895040/
https://www.ncbi.nlm.nih.gov/pubmed/24466056
http://dx.doi.org/10.1371/journal.pone.0086365

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3895040/
https://www.ncbi.nlm.nih.gov/pubmed/24466056
http://dx.doi.org/10.1371/journal.pone.0086365

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