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Coupling of Hedgehog and Hippo pathways promotes stem cell maintenance by stimulating proliferation

It is essential to define the mechanisms by which external signals regulate adult stem cell numbers, stem cell maintenance, and stem cell proliferation to guide regenerative stem cell therapies and to understand better how cancers originate in stem cells. In this paper, we show that Hedgehog (Hh) si...

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Detalles Bibliográficos
Autores principales: Huang, Jianhua, Kalderon, Daniel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4018789/
https://www.ncbi.nlm.nih.gov/pubmed/24798736
http://dx.doi.org/10.1083/jcb.201309141