Rational design of cyclopropane-based chiral PHOX ligands for intermolecular asymmetric Heck reaction

A novel class of chiral phosphanyl-oxazoline (PHOX) ligands with a conformationally rigid cyclopropyl backbone was synthesized and tested in the intermolecular asymmetric Heck reaction. Mechanistic modelling and crystallographic studies were used to predict the optimal ligand structure and helped to...

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Detalles Bibliográficos
Autores principales: Rubina, Marina, Sherrill, William M, Barkov, Alexey Yu, Rubin, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Beilstein-Institut 2014
Materias:
Full Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143097/
https://www.ncbi.nlm.nih.gov/pubmed/25161709
http://dx.doi.org/10.3762/bjoc.10.158

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4143097/
https://www.ncbi.nlm.nih.gov/pubmed/25161709
http://dx.doi.org/10.3762/bjoc.10.158

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