Using Multivariable Mendelian Randomization to Disentangle the Causal Effects of Lipid Fractions
BACKGROUND: Previous Mendelian randomization studies have suggested that, while low-density lipoprotein cholesterol (LDL-c) and triglycerides are causally implicated in coronary artery disease (CAD) risk, high-density lipoprotein cholesterol (HDL-c) may not be, with causal effect estimates compatibl...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4193746/ https://www.ncbi.nlm.nih.gov/pubmed/25302496 http://dx.doi.org/10.1371/journal.pone.0108891 |