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Silencing airway epithelial cell-derived hepcidin exacerbates sepsis-induced acute lung injury
INTRODUCTION: The production of antimicrobial peptides by airway epithelial cells is an important component of the innate immune response to pulmonary infection and inflammation. Hepcidin is a β-defensin-like antimicrobial peptide and acts as a principal iron regulatory hormone. Hepcidin is mostly p...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4243715/ https://www.ncbi.nlm.nih.gov/pubmed/25096529 http://dx.doi.org/10.1186/s13054-014-0470-8 |