Small Molecule Substrate Phosphorylation Site Inhibitors of Protein Kinases: Approaches and Challenges
[Image: see text] Protein kinases are important mediators of cellular communication and attractive drug targets for many diseases. Although success has been achieved with developing ATP-competitive kinase inhibitors, the disadvantages of ATP-competitive inhibitors have led to increased interest in t...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Chemical
Society
2014
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4301090/ https://www.ncbi.nlm.nih.gov/pubmed/25494294 http://dx.doi.org/10.1021/cb5008376 |