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Repeated nitrous oxide exposure in rats causes a thermoregulatory sign-reversal with concurrent activation of opposing thermoregulatory effectors
Initial administration of 60% nitrous oxide (N(2)O) to rats at an ambient temperature of 21°C decreases core temperature (Tc), primarily via increased heat loss (HL). Over repeated N(2)O administrations, rats first develop tolerance to this hypothermia and subsequently exhibit hyperthermia (a sign-r...
Autores principales: | Ramsay, Douglas S, Woods, Stephen C, Kaiyala, Karl J |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4414259/ https://www.ncbi.nlm.nih.gov/pubmed/25938127 http://dx.doi.org/10.4161/23328940.2014.944809 |
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