Pharmacological Repression of PPARγ Promotes Osteogenesis

The nuclear receptor peroxisome proliferator-activated receptor gamma (PPARγ) is the master regulator of adipogenesis and the pharmacological target of the thiazolidinedione (TZD) class of insulin sensitizers. Activation of PPARγ by TZDs promotes adipogenesis at the expense of osteoblast formation,...

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Detalles Bibliográficos
Autores principales: Marciano, David P., Kuruvilla, Dana S., Boregowda, Siddaraju V., Asteian, Alice, Hughes, Travis S., Garcia-Ordonez, Ruben, Corzo, Cesar A., Khan, Tanya M., Novick, Scott J., Park, HaJeung, Kojetin, Douglas J., Phinney, Donald G., Bruning, John B., Kamenecka, Theodore M., Griffin, Patrick R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471882/
https://www.ncbi.nlm.nih.gov/pubmed/26068133
http://dx.doi.org/10.1038/ncomms8443

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4471882/
https://www.ncbi.nlm.nih.gov/pubmed/26068133
http://dx.doi.org/10.1038/ncomms8443

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