UV irradiation/cold shock-mediated apoptosis is switched to bubbling cell death at low temperatures

When COS7 fibroblasts and other cells were exposed to UVC irradiation and cold shock at 4°C for 5 min, rapid upregulation and nuclear accumulation of NOS2, p53, WWOX, and TRAF2 occurred in 10–30 min. By time-lapse microscopy, an enlarging gas bubble containing nitric oxide (NO) was formed in the nuc...

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Detalles Bibliográficos
Autores principales: Chen, Szu-Jung, Lin, Pei-Wen, Lin, Hsin-Ping, Huang, Shenq-Shyang, Lai, Feng-Jie, Sheu, Hamm-Ming, Hsu, Li-Jin, Chang, Nan-Shan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480731/
https://www.ncbi.nlm.nih.gov/pubmed/25779665

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4480731/
https://www.ncbi.nlm.nih.gov/pubmed/25779665

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