HMGB1 promotes the activation of NLRP3 and caspase-8 inflammasomes via NF-κB pathway in acute glaucoma

BACKGROUND: Acute glaucoma is a significantly sight-threatening cause of irreversible blindness in the world characterized by a sudden and substantial intraocular pressure (IOP) increase and subsequent retinal ganglion cell (RGC) death. This study aims to explore the role of high-mobility group box...

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Detalles Bibliográficos
Autores principales: Chi, Wei, Chen, Hongrui, Li, Fei, Zhu, Yingting, Yin, Wei, Zhuo, Yehong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518626/
https://www.ncbi.nlm.nih.gov/pubmed/26224068
http://dx.doi.org/10.1186/s12974-015-0360-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4518626/
https://www.ncbi.nlm.nih.gov/pubmed/26224068
http://dx.doi.org/10.1186/s12974-015-0360-2

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