The natural compound forskolin synergizes with dexamethasone to induce cell death in myeloma cells via BIM

We have previously demonstrated that activation of the cyclic adenosine monophosphate (cAMP) pathway kills multiple myeloma (MM) cells both in vitro and in vivo. In the present study we have investigated the potential of enhancing the killing of MM cell lines and primary MM cells by combining the cA...

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Detalles Bibliográficos
Autores principales: Follin-Arbelet, Virginie, Misund, Kristine, Hallan Naderi, Elin, Ugland, Hege, Sundan, Anders, Kiil Blomhoff, Heidi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4549684/
https://www.ncbi.nlm.nih.gov/pubmed/26306624
http://dx.doi.org/10.1038/srep13001