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Context-dependent utilization of serine in cancer

Serine and glycine have diverse biological functions but the general and context-dependent utilization of these nutrients in cancer is poorly understood. Our recent work integrates genomics data and isotope tracing using computational tools to study serine utilization across multiple cancer and norm...

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Detalles Bibliográficos
Autores principales: Mehrmohamadi, Mahya, Locasale, Jason W
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4635483/
https://www.ncbi.nlm.nih.gov/pubmed/26550606
http://dx.doi.org/10.1080/23723556.2014.996418
Descripción
Sumario:Serine and glycine have diverse biological functions but the general and context-dependent utilization of these nutrients in cancer is poorly understood. Our recent work integrates genomics data and isotope tracing using computational tools to study serine utilization across multiple cancer and normal human samples.