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Simultaneous quantification of artesunate and mefloquine in fixed-dose combination tablets by multivariate calibration with middle infrared spectroscopy and partial least squares regression
BACKGROUND: Malaria is one of the most lethal and life-threatening infectious diseases in the world, causing more than half a million deaths annually. Treatment with mefloquine and artesunate is currently recommended by the World Health Organization, and was historically the first artemisinin-based...
Autores principales: | Marson, Breno Maurício, de Oliveira Vilhena, Raquel, de Souza Madeira, Camilla Regina, Pontes, Flávia Lada Degaut, Piantavini, Mário Sérgio, Pontarolo, Roberto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4765072/ https://www.ncbi.nlm.nih.gov/pubmed/26911371 http://dx.doi.org/10.1186/s12936-016-1157-1 |
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