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Evidence for a Negative Cooperativity between eIF5A and eEF2 on Binding to the Ribosome
eIF5A is the only protein known to contain the essential and unique amino acid residue hypusine. eIF5A functions in both translation initiation due to its stimulation of methionyl-puromycin synthesis and translation elongation, being highly required for peptide-bound formation of specific ribosome s...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845985/ https://www.ncbi.nlm.nih.gov/pubmed/27115996 http://dx.doi.org/10.1371/journal.pone.0154205 |