Evidence for a Negative Cooperativity between eIF5A and eEF2 on Binding to the Ribosome

eIF5A is the only protein known to contain the essential and unique amino acid residue hypusine. eIF5A functions in both translation initiation due to its stimulation of methionyl-puromycin synthesis and translation elongation, being highly required for peptide-bound formation of specific ribosome s...

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Detalles Bibliográficos
Autores principales: Rossi, Danuza, Barbosa, Natalia M., Galvão, Fabio C., Boldrin, Paulo E. G., Hershey, John W. B., Zanelli, Cleslei F., Fraser, Christopher S., Valentini, Sandro R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845985/
https://www.ncbi.nlm.nih.gov/pubmed/27115996
http://dx.doi.org/10.1371/journal.pone.0154205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4845985/
https://www.ncbi.nlm.nih.gov/pubmed/27115996
http://dx.doi.org/10.1371/journal.pone.0154205

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