CAR models: next-generation CAR modifications for enhanced T-cell function

T cells genetically targeted with a chimeric antigen receptor (CAR) to B-cell malignancies have demonstrated tremendous clinical outcomes. With the proof in principle for CAR T cells as a therapy for B-cell malignancies being established, current and future research is being focused on adapting CAR...

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Detalles Bibliográficos
Autores principales: Abate-Daga, Daniel, Davila, Marco L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871190/
https://www.ncbi.nlm.nih.gov/pubmed/27231717
http://dx.doi.org/10.1038/mto.2016.14

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4871190/
https://www.ncbi.nlm.nih.gov/pubmed/27231717
http://dx.doi.org/10.1038/mto.2016.14

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