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Effects of odanacatib on bone matrix mineralization in rhesus monkeys are similar to those of alendronate

Odanacatib (ODN) is a selective and reversible inhibitor of cathepsin K which is an important enzyme for the degradation of collagen I. Aim of the present work was the head-to-head comparison between the effects of ODN and alendronate (ALN) on bone mineralization density distribution (BMDD), based o...

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Detalles Bibliográficos
Autores principales: Misof, Barbara M., Roschger, Paul, Chen, Charles, Pickarski, Maureen, Messmer, Phaedra, Klaushofer, Klaus, Duong, Le T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4926807/
https://www.ncbi.nlm.nih.gov/pubmed/28326348
http://dx.doi.org/10.1016/j.bonr.2016.03.001