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Identification of an Essential Region for Translocation of Clostridium difficile Toxin B

Clostridium difficile toxin A (TcdA) and toxin B (TcdB) are the major virulence factors involved in C. difficile-associated diarrhea and pseudomembranous colitis. TcdA and TcdB both contain at least four distinct domains: the glucosyltransferase domain, cysteine protease domain, receptor binding dom...

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Detalles Bibliográficos
Autores principales: Chen, Shuyi, Wang, Haiying, Gu, Huawei, Sun, Chunli, Li, Shan, Feng, Hanping, Wang, Jufang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4999857/
https://www.ncbi.nlm.nih.gov/pubmed/27537911
http://dx.doi.org/10.3390/toxins8080241