CellMapper: rapid and accurate inference of gene expression in difficult-to-isolate cell types

We present a sensitive approach to predict genes expressed selectively in specific cell types, by searching publicly available expression data for genes with a similar expression profile to known cell-specific markers. Our method, CellMapper, strongly outperforms previous computational algorithms to...

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Detalles Bibliográficos
Autores principales: Nelms, Bradlee D., Waldron, Levi, Barrera, Luis A., Weflen, Andrew W., Goettel, Jeremy A., Guo, Guoji, Montgomery, Robert K., Neutra, Marian R., Breault, David T., Snapper, Scott B., Orkin, Stuart H., Bulyk, Martha L., Huttenhower, Curtis, Lencer, Wayne I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Method
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5043525/
https://www.ncbi.nlm.nih.gov/pubmed/27687735
http://dx.doi.org/10.1186/s13059-016-1062-5

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