Ontogeny of Unstable Chromosomes Generated by Telomere Error in Budding Yeast

DNA replication errors at certain sites in the genome initiate chromosome instability that ultimately leads to stable genomic rearrangements. Where instability begins is often unclear. And, early instability may form unstable chromosome intermediates whose transient nature also hinders mechanistic u...

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Detalles Bibliográficos
Autores principales: Beyer, Tracey, Weinert, Ted
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065131/
https://www.ncbi.nlm.nih.gov/pubmed/27716774
http://dx.doi.org/10.1371/journal.pgen.1006345