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Jump into a New Fold—A Homology Based Model for the ABCG2/BCRP Multidrug Transporter
ABCG2/BCRP is a membrane protein, involved in xenobiotic and endobiotic transport in key pharmacological barriers and drug metabolizing organs, in the protection of stem cells, and in multidrug resistance of cancer. Pharmacogenetic studies implicated the role of ABCG2 in response to widely used medi...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5065228/ https://www.ncbi.nlm.nih.gov/pubmed/27741279 http://dx.doi.org/10.1371/journal.pone.0164426 |