Quantitative cross-linking/mass spectrometry reveals subtle protein conformational changes
Quantitative cross-linking/mass spectrometry (QCLMS) probes protein structural dynamics in solution by quantitatively comparing the yields of cross-links between different conformational statuses. We have used QCLMS to understand the final maturation step of the proteasome lid and also to elucidate...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000Research
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5140025/ https://www.ncbi.nlm.nih.gov/pubmed/27976756 http://dx.doi.org/10.12688/wellcomeopenres.9896.1 |