Targeted activation of AMPK by GSK621 ameliorates H(2)O(2)-induced damages in osteoblasts
GSK621 is a novel AMP-activated protein kinase (AMPK) activator. This study tested its potential cytoprotective effect in hydrogen peroxide (H(2)O(2))-treated osteoblasts. In cultured MC3T3-E1 osteoblastic cells and primary murine osteoblasts, GSK621 significantly attenuated H(2)O(2)-induced cell de...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5354679/ https://www.ncbi.nlm.nih.gov/pubmed/28060740 http://dx.doi.org/10.18632/oncotarget.14454 |