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The importance of N-glycosylation on β(3) integrin ligand binding and conformational regulation
N-glycosylations can regulate the adhesive function of integrins. Great variations in both the number and distribution of N-glycosylation sites are found in the 18 α and 8 β integrin subunits. Crystal structures of α(IIb)β(3) and α(V)β(3) have resolved the precise structural location of each N-glyca...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5498496/ https://www.ncbi.nlm.nih.gov/pubmed/28680094 http://dx.doi.org/10.1038/s41598-017-04844-w |