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Entamoeba histolytica-Induced Mucin Exocytosis Is Mediated by VAMP8 and Is Critical in Mucosal Innate Host Defense

Intestinal mucus secretion is critical in maintaining mucosal host defense against a myriad of pathogens by preventing direct association with the epithelium. Entamoeba histolytica specifically binds colonic MUC2 mucin and also induces potent hypersecretion from goblet cells; however, characterizati...

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Detalles Bibliográficos
Autores principales: Cornick, Steve, Moreau, France, Gaisano, Herbert Y., Chadee, Kris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5626970/
https://www.ncbi.nlm.nih.gov/pubmed/28974617
http://dx.doi.org/10.1128/mBio.01323-17