p53 upregulates PLCε-IP3-Ca(2+) pathway and inhibits autophagy through its target gene Rap2B

The tumor suppressor p53 plays a pivotal role in numerous cellular responses as it regulates cell proliferation, metabolism, cellular growth, and autophagy. In order to identify novel p53 target genes, we utilized an unbiased microarray approach and identified Rap2B as a robust candidate, which belo...

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Detalles Bibliográficos
Autores principales: Di, Jiehui, Tang, Juanjuan, Qian, Heya, Franklin, Derek A., Deisenroth, Chad, Itahana, Yoko, Zheng, Junnian, Zhang, Yanping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Priority Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630284/
https://www.ncbi.nlm.nih.gov/pubmed/29029384
http://dx.doi.org/10.18632/oncotarget.18112

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630284/
https://www.ncbi.nlm.nih.gov/pubmed/29029384
http://dx.doi.org/10.18632/oncotarget.18112

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