Overexpression of ceramide synthase 1 increases C18-ceramide and leads to lethal autophagy in human glioma

Ceramide synthase 1 (CERS1) is the most highly expressed CERS in the central nervous system, and ceramide with an 18-carbon–containing fatty acid chain (C18-ceramide) in the brain plays important roles in signaling and sphingolipid development. However, the roles of CERS1 and C18-ceramide in glioma...

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Detalles Bibliográficos
Autores principales: Wang, Zheng, Wen, Lijun, Zhu, Fei, Wang, Yanping, Xie, Qing, Chen, Zijun, Li, Yunsen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732784/
https://www.ncbi.nlm.nih.gov/pubmed/29262618
http://dx.doi.org/10.18632/oncotarget.21955