Overexpression of ceramide synthase 1 increases C18-ceramide and leads to lethal autophagy in human glioma
Ceramide synthase 1 (CERS1) is the most highly expressed CERS in the central nervous system, and ceramide with an 18-carbon–containing fatty acid chain (C18-ceramide) in the brain plays important roles in signaling and sphingolipid development. However, the roles of CERS1 and C18-ceramide in glioma...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5732784/ https://www.ncbi.nlm.nih.gov/pubmed/29262618 http://dx.doi.org/10.18632/oncotarget.21955 |