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P2X7 receptor regulates osteoclast function and bone loss in a mouse model of osteoporosis

Post-menopausal osteoporosis is a condition that affects millions worldwide and places a huge socio-economic burden on society. Previous research has shown an association of loss of function SNPs in the gene for the purinergic receptor P2X7R with low bone mineral density, increased rates of bone los...

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Detalles Bibliográficos
Autores principales: Wang, Ning, Agrawal, Ankita, Jørgensen, Niklas Rye, Gartland, Alison
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5823935/
https://www.ncbi.nlm.nih.gov/pubmed/29472582
http://dx.doi.org/10.1038/s41598-018-21574-9