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Neisseria Heparin Binding Antigen is targeted by the human alternative pathway C3-convertase
Neisserial Heparin Binding Antigen (NHBA) is a surface-exposed lipoprotein specific for Neisseria and constitutes one of the three main protein antigens of the Bexsero vaccine. Meningococcal and human proteases, cleave NHBA protein upstream or downstream of a conserved Arg-rich region, respectively....
Autores principales: | Di Fede, Martina, Biagini, Massimiliano, Cartocci, Elena, Parillo, Carlo, Greco, Alessandra, Martinelli, Manuele, Marchi, Sara, Pezzicoli, Alfredo, Delany, Isabel, Rossi Paccani, Silvia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5868813/ https://www.ncbi.nlm.nih.gov/pubmed/29579105 http://dx.doi.org/10.1371/journal.pone.0194662 |
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