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Host-mediated selection impacts the diversity of Plasmodium falciparum antigens within infections
Host immunity exerts strong selective pressure on pathogens. Population-level genetic analysis can identify signatures of this selection, but these signatures reflect the net selective effect of all hosts and vectors in a population. In contrast, analysis of pathogen diversity within hosts provides...
Autores principales: | Early, Angela M., Lievens, Marc, MacInnis, Bronwyn L., Ockenhouse, Christian F., Volkman, Sarah K., Adjei, Samuel, Agbenyega, Tsiri, Ansong, Daniel, Gondi, Stacey, Greenwood, Brian, Hamel, Mary, Odero, Chris, Otieno, Kephas, Otieno, Walter, Owusu-Agyei, Seth, Asante, Kwaku Poku, Sorgho, Hermann, Tina, Lucas, Tinto, Halidou, Valea, Innocent, Wirth, Dyann F., Neafsey, Daniel E. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5895824/ https://www.ncbi.nlm.nih.gov/pubmed/29643376 http://dx.doi.org/10.1038/s41467-018-03807-7 |
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