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Hippo pathway coactivators Yap and Taz are required to coordinate mammalian liver regeneration

The mammalian liver has a remarkable capacity for repair following injury. Removal of up to two-third of liver mass results in a series of events that include extracellular matrix remodeling, coordinated hepatic cell cycle re-entry, restoration of liver mass and tissue remodeling to return the damag...

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Detalles Bibliográficos
Autores principales: Lu, Li, Finegold, Milton J, Johnson, Randy L
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5992983/
https://www.ncbi.nlm.nih.gov/pubmed/29303509
http://dx.doi.org/10.1038/emm.2017.205