Cargando…

ETV4 transcription factor and MMP13 metalloprotease are interplaying actors of breast tumorigenesis

BACKGROUND: The ETS transcription factor ETV4 is involved in the main steps of organogenesis and is also a significant mediator of tumorigenesis and metastasis, such as in breast cancer. Indeed, ETV4 is overexpressed in breast tumors and is associated with distant metastasis and poor prognosis. Howe...

Descripción completa

Detalles Bibliográficos
Autores principales: Dumortier, Mandy, Ladam, Franck, Damour, Isabelle, Vacher, Sophie, Bièche, Ivan, Marchand, Nathalie, de Launoit, Yvan, Tulasne, David, Chotteau-Lelièvre, Anne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6042225/
https://www.ncbi.nlm.nih.gov/pubmed/29996935
http://dx.doi.org/10.1186/s13058-018-0992-0