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Identification of brain metastasis genes and therapeutic evaluation of histone deacetylase inhibitors in a clinically relevant model of breast cancer brain metastasis

Breast cancer brain metastases remain largely incurable. Although several mouse models have been developed to investigate the genes and mechanisms regulating breast cancer brain metastasis, these models often lack clinical relevance since they require the use of immunocompromised mice and/or are poo...

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Detalles Bibliográficos
Autores principales: Kim, Soo-Hyun, Redvers, Richard P., Chi, Lap Hing, Ling, Xiawei, Lucke, Andrew J., Reid, Robert C., Fairlie, David P., Martin, Ana Carolina Baptista Moreno, Anderson, Robin L., Denoyer, Delphine, Pouliot, Normand
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6078399/
https://www.ncbi.nlm.nih.gov/pubmed/29784888
http://dx.doi.org/10.1242/dmm.034850