Structural basis for promotion of duodenal iron absorption by enteric ferric reductase with ascorbate

Dietary iron absorption is regulated by duodenal cytochrome b (Dcytb), an integral membrane protein that catalyzes reduction of nonheme Fe(3+) by electron transfer from ascorbate across the membrane. This step is essential to enable iron uptake by the divalent metal transporter. Here we report the c...

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Detalles Bibliográficos
Autores principales: Ganasen, Menega, Togashi, Hiromi, Takeda, Hanae, Asakura, Honami, Tosha, Takehiko, Yamashita, Keitaro, Hirata, Kunio, Nariai, Yuko, Urano, Takeshi, Yuan, Xiaojing, Hamza, Iqbal, Mauk, A. Grant, Shiro, Yoshitsugu, Sugimoto, Hiroshi, Sawai, Hitomi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6123691/
https://www.ncbi.nlm.nih.gov/pubmed/30272000
http://dx.doi.org/10.1038/s42003-018-0121-8

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