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Gut Barrier Dysfunction—A Primary Defect in Twins with Crohn’s Disease Predominantly Caused by Genetic Predisposition
BACKGROUND AND AIMS: The aetiology of Crohn’s disease is poorly understood. By investigating twin pairs discordant for Crohn’s disease, we aimed to assess whether the dysregulated barrier represents a cause or a consequence of inflammation and to evaluate the impact of genetic predisposition on barr...
Autores principales: | Keita, Åsa V, Lindqvist, Carl Mårten, Öst, Åke, Magana, Carlos D L, Schoultz, Ida, Halfvarson, Jonas |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6225972/ https://www.ncbi.nlm.nih.gov/pubmed/29659773 http://dx.doi.org/10.1093/ecco-jcc/jjy045 |
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