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MCT2 mediates concentration-dependent inhibition of glutamine metabolism by MOG
α-Ketoglutarate (αKG) is a key node in many important metabolic pathways. The αKG analogue N-oxalylglycine (NOG) and its cell-permeable pro-drug dimethyloxalylglycine (DMOG) are extensively used to inhibit αKG-dependent dioxygenases. However, whether NOG interference with other αKG-dependent process...
Autores principales: | , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6298574/ https://www.ncbi.nlm.nih.gov/pubmed/30297875 http://dx.doi.org/10.1038/s41589-018-0136-y |