BCL2-Family Dysregulation in B-Cell Malignancies: From Gene Expression Regulation to a Targeted Therapy Biomarker

BCL2-family proteins have a central role in the mitochondrial apoptosis machinery and their expression is known to be deregulated in many cancer types. Effort in the development of small molecules that selectively target anti-apoptotic members of this family i.e., Bcl-2, Bcl-xL, Mcl-1 recently opene...

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Detalles Bibliográficos
Autores principales: Tessoulin, Benoît, Papin, Antonin, Gomez-Bougie, Patricia, Bellanger, Celine, Amiot, Martine, Pellat-Deceunynck, Catherine, Chiron, David
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2019
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330761/
https://www.ncbi.nlm.nih.gov/pubmed/30666297
http://dx.doi.org/10.3389/fonc.2018.00645

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6330761/
https://www.ncbi.nlm.nih.gov/pubmed/30666297
http://dx.doi.org/10.3389/fonc.2018.00645

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