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Osimertinib Treatment Was Unsuccessful for Lung Adenocarcinoma with G719S, S768I, and T790M Mutations

Epidermal growth factor receptor (EGFR) T790M mutations are the most frequent mechanism of resistance to first- and second-generation tyrosine kinase inhibitors, and osimertinib is an effective treatment for patients with both EGFR-activating mutations and T790M resistance mutations. We describe the...

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Detalles Bibliográficos
Autores principales:	Nasu, Shingo, Shiroyama, Takayuki, Morita, Satomu, Takata, So, Takada, Hiromune, Masuhiro, Kentaro, Tanaka, Ayako, Morishita, Naoko, Suzuki, Hidekazu, Okamoto, Norio, Hirashima, Tomonori
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Japanese Society of Internal Medicine 2018
Materias:	Case Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6355418/ https://www.ncbi.nlm.nih.gov/pubmed/30146570 http://dx.doi.org/10.2169/internalmedicine.0923-18

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