Cargando…
Off- and on-target effects of genome editing in mouse embryos
Clustered regularly interspaced short palindromic repeats (CRISPR)-Cas-based genome editing technology has enabled manipulation of the embryonic genome. Unbiased whole genome sequencing comparing parents to progeny has revealed that the rate of Cas9-induced mutagenesis in mouse embryos is indistingu...
Autores principales: | AYABE, Shinya, NAKASHIMA, Kenichi, YOSHIKI, Atsushi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Society for Reproduction and Development
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6379761/ https://www.ncbi.nlm.nih.gov/pubmed/30518723 http://dx.doi.org/10.1262/jrd.2018-128 |
Ejemplares similares
-
Rabbit models for biomedical research revisited via genome editing approaches
por: HONDA, Arata, et al.
Publicado: (2017) -
A unique mechanism regulating gene expression in 1-cell embryos
por: YAMAMOTO, Ryoma, et al.
Publicado: (2016) -
Challenges to increasing targeting efficiency in genome engineering
por: HORII, Takuro, et al.
Publicado: (2015) -
Transfer of a single embryo versus drainage of subordinate follicles to prevent twin pregnancies in dairy cows. Why not both?
por: LÓPEZ-GATIUS, Fernando, et al.
Publicado: (2020) -
In quest of genomic treasure
por: INOUE, Kimiko, et al.
Publicado: (2015)