Tandem Peterson olefination and chemoselective asymmetric hydrogenation of β-hydroxy silanes

Here, we report the first Ir–N,P complex catalyzed tandem Peterson olefination and asymmetric hydrogenation of β-hydroxy silanes. This reaction resulted in the formation of chiral alkanes in high isolated yields (up to 99%) and excellent enantioselectivity (up to 99% ee) under mild conditions. Modif...

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Detalles Bibliográficos
Autores principales: Krajangsri, Suppachai, Wu, Haibo, Liu, Jianguo, Rabten, Wangchuk, Singh, Thishana, Andersson, Pher G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Royal Society of Chemistry 2019
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438149/
https://www.ncbi.nlm.nih.gov/pubmed/30996960
http://dx.doi.org/10.1039/c8sc05261a

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6438149/
https://www.ncbi.nlm.nih.gov/pubmed/30996960
http://dx.doi.org/10.1039/c8sc05261a

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