Downregulation of CHIP promotes ovarian cancer metastasis by inducing Snail‐mediated epithelial–mesenchymal transition

The epithelial–mesenchymal transition (EMT) plays a pivotal role in the conversion of early‐stage tumors into invasive malignancies. The transcription factor Snail, an extremely unstable protein whose subcellular levels are regulated by many E3 ubiquitin ligases, promotes EMT as well as associated p...

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Detalles Bibliográficos
Autores principales: Park, Sun‐Mi, Park, Seung‐Ho, Ryu, Ki‐Jun, Kim, In‐Kyu, Han, Hyeontak, Kim, Hyo‐Jin, Kim, Seon‐Hee, Hong, Keun‐Seok, Kim, Hyemin, Kim, Minju, Cho, Bok Im, Heo, Jeong Doo, Kim, Na Hyun, Hwang, Eun Mi, Park, Jae‐Yong, Yook, Jong In, Cho, Hee Jun, Hwangbo, Cheol, Kim, Kwang Dong, Song, Hoseok, Yoo, Jiyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6487736/
https://www.ncbi.nlm.nih.gov/pubmed/30927556
http://dx.doi.org/10.1002/1878-0261.12485

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