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Fast and robust deconvolution of tumor infiltrating lymphocyte from expression profiles using least trimmed squares
Gene-expression deconvolution is used to quantify different types of cells in a mixed population. It provides a highly promising solution to rapidly characterize the tumor-infiltrating immune landscape and identify cold cancers. However, a major challenge is that gene-expression data are frequently...
Autores principales: | Hao, Yuning, Yan, Ming, Heath, Blake R., Lei, Yu L., Xie, Yuying |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6522071/ https://www.ncbi.nlm.nih.gov/pubmed/31059559 http://dx.doi.org/10.1371/journal.pcbi.1006976 |
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