CyclinD1 inhibits dicer and crucial miRNA expression by chromatin modification to promote the progression of intrahepatic cholangiocarcinoma

BACKGROUND: CyclinD1 is crucial for cell cycling and can regulate the expression of Dicer, a crucial regulator of microRNA maturation. However, little is known on how CyclinD1 regulates Dicer and miRNA expression, and the progression of intrahepatic cholangiocarcinoma (ICC). METHODS: The expression...

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Detalles Bibliográficos
Autores principales: Qi, Yongqiang, Wang, Da, Huang, Wenhua, Wang, Bing, Huang, Di, Xiong, Fei, Chen, Xiaoping, Chen, Yongjun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2019
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781400/
https://www.ncbi.nlm.nih.gov/pubmed/31590696
http://dx.doi.org/10.1186/s13046-019-1415-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6781400/
https://www.ncbi.nlm.nih.gov/pubmed/31590696
http://dx.doi.org/10.1186/s13046-019-1415-5

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