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Long noncoding RNA GAS5 inhibits cell proliferation and fibrosis in diabetic nephropathy by sponging miR-221 and modulating SIRT1 expression
Diabetic nephropathy (DN) is one of the leading causes of end-stage renal diseases worldwide. This study is designed to investigate the underlying function and mechanism of a novel lncRNA GAS5 in the progression of DN. We found that lncRNA GAS5 expression level was decreased in type 2 diabetes (T2D)...
Autores principales: | Ge, Xiaoxu, Xu, Bojin, Xu, Wenwei, Xia, Lili, Xu, Zhongqin, Shen, Lisha, Peng, Wenfang, Huang, Shan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals
2019
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6834398/ https://www.ncbi.nlm.nih.gov/pubmed/31631065 http://dx.doi.org/10.18632/aging.102249 |
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