The G Protein-Coupled Bile Acid Receptor TGR5 (Gpbar1) Modulates Endothelin-1 Signaling in Liver

TGR5 (Gpbar1) is a G protein-coupled receptor responsive to bile acids (BAs), which is expressed in different non-parenchymal cells of the liver, including biliary epithelial cells, liver-resident macrophages, sinusoidal endothelial cells (LSECs), and activated hepatic stellate cells (HSCs). Mice wi...

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Detalles Bibliográficos
Autores principales: Klindt, Caroline, Reich, Maria, Hellwig, Birte, Stindt, Jan, Rahnenführer, Jörg, Hengstler, Jan G., Köhrer, Karl, Schoonjans, Kristina, Häussinger, Dieter, Keitel, Verena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6912679/
https://www.ncbi.nlm.nih.gov/pubmed/31752395
http://dx.doi.org/10.3390/cells8111467